DBCO-PEG-Biotin

Product Information

Product Name: DBCO-PEG-Biotin

Synonyms:  Dibenzocyclooctyne-PEG-Biotin, DBCO Poly(ethylene glycol) Biotin, DBCO PEG

Specifications

Purity: 95%+

PDI：1.05max

Molecular Weight: 5K, 10K, 20K, 40K

Package: 1G,5G,10G,20G,25G,50G,100G,250G,500G

Quality Control

1H-NMR, GPC, MALDI - TOF, COA

Storage condition

Kept at -25±5 ºC under the inert atmosphere.

Usage

DBCO-PEG-Biotin from NBC (Shanghai) Chemical Co.,Ltd are high purity with low dispersion polyethylene glycol (PEG) derivatives, DBCO (dibenzocycolctyne) PEG Biotin derivatives can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics and stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.